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Jacob Lorenzo-Morales Selected Research

Amebiasis (Amoebiasis)

8/2019Ursolic Acid Derivatives as Potential Agents Against Acanthamoeba Spp.
2/2019Evaluation of the sensitivity to chlorhexidine, voriconazole and itraconazole of T4 genotype Acanthamoeba isolated from Mexico.
12/2017In vitro amoebicidal and antioxidant activities of some Tunisian seaweeds.
6/2017Amoebicidal activity of α-bisabolol, the main sesquiterpene in chamomile (Matricaria recutita L.) essential oil against the trophozoite stage of Acanthamoeba castellani Neff.
1/2017Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts.
1/2015An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment.
11/2014Bioassay guided isolation and identification of anti-Acanthamoeba compounds from Tunisian olive leaf extracts.
2/2014Voriconazole as a first-line treatment against potentially pathogenic Acanthamoeba strains from Peru.
1/2013Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections.

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Jacob Lorenzo-Morales Research Topics

Disease

21Infections
06/2022 - 08/2007
16Cysts
02/2022 - 11/2006
14Acanthamoeba Keratitis
06/2022 - 04/2011
9Amebiasis (Amoebiasis)
08/2019 - 01/2013
5Keratitis
12/2017 - 04/2011
4Encephalitis (Encephalitis, Rasmussen)
12/2017 - 12/2009
3Leishmaniasis
07/2016 - 06/2014
2COVID-19
11/2021 - 06/2020
2Wounds and Injuries (Trauma)
12/2020 - 10/2012
2Blindness (Hysterical Blindness)
06/2018 - 02/2016
2Neoplasms (Cancer)
12/2017 - 04/2007
2Acquired Immunodeficiency Syndrome (AIDS)
09/2015 - 11/2014
2Fever (Fevers)
10/2014 - 08/2013
2Malaria
12/2013 - 08/2013
2Coinfection
10/2012 - 09/2010
2Osteosarcoma (Osteogenic Sarcoma)
12/2010 - 09/2010
1Meningoencephalitis
06/2022
1Necrosis
01/2022
1Cataract (Cataracts)
10/2021
1Inflammation (Inflammations)
10/2020
1Dry Eye Syndromes (Dry Eye Syndrome)
01/2018
1Bacterial Infections (Bacterial Infection)
12/2017
1Glaucoma
12/2017
1Mycoses (Diseases, Fungus)
12/2017
1Pneumonia (Pneumonitis)
12/2017
1Opportunistic Infections (Opportunistic Infection)
12/2017
1Renal Insufficiency (Renal Failure)
11/2017
1Erysipelas
11/2014
1Neglected Diseases
06/2014
1Toxoplasmosis
02/2014
1Scleritis (Episcleritis)
12/2013
1Reinfection
03/2008

Drug/Important Bio-Agent (IBA)

4Pharmaceutical PreparationsIBA
08/2021 - 04/2007
4Voriconazole (Vfend)FDA LinkGeneric
02/2019 - 10/2012
3ChlorhexidineIBA
01/2022 - 02/2014
3Ophthalmic Solutions (Eye Drops)IBA
01/2021 - 04/2011
3Adenosine Triphosphate (ATP)IBA
01/2021 - 12/2017
3Anti-Bacterial Agents (Antibiotics)IBA
12/2017 - 11/2014
3AcidsIBA
11/2014 - 03/2008
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
02/2022 - 01/2013
2SilverIBA
05/2021 - 05/2020
2Contact Lens Solutions (Contact Lens Solution)IBA
05/2021 - 12/2020
2SoilIBA
01/2021 - 12/2009
2DNA (Deoxyribonucleic Acid)IBA
01/2021 - 12/2020
2SolutionsIBA
12/2020 - 01/2015
2Glycogen Phosphorylase (Phosphorylase, Glycogen)IBA
01/2017 - 12/2010
2AntibodiesIBA
11/2014 - 02/2014
1Rosuvastatin Calcium (Crestor)FDA Link
02/2022
1cerivastatin (Kazak)FDA Link
02/2022
1pitavastatin (itavastatin)FDA Link
02/2022
1polihexanideIBA
01/2022
1RNA (Ribonucleic Acid)IBA
11/2021
1Ethanol (Ethyl Alcohol)IBA
07/2021
1Dexamethasone Drug Combination TobramycinFDA LinkGeneric
01/2021
1Atorvastatin (Lipitor)FDA Link
10/2020
1FluvastatinFDA Link
10/2020
1Antiviral Agents (Antivirals)IBA
06/2020
1Ursolic AcidIBA
08/2019
1Itraconazole (Sporanox)FDA LinkGeneric
02/2019
1SuspensionsIBA
01/2018
1Volatile Oils (Essential Oils)IBA
12/2017
1Biological ProductsIBA
12/2017
1ChromatinIBA
12/2017
1Timolol (Blocadren)FDA LinkGeneric
12/2017
1AntioxidantsIBA
12/2017
1bisabolol (levomenol)IBA
06/2017
1Caffeine (No Doz)FDA LinkGeneric
01/2017
1maslinic acidIBA
01/2017
1hexaazatrinaphthyleneIBA
07/2016
1oleuropeinIBA
11/2014
1VaccinesIBA
11/2014
1Doxycycline (Periostat)FDA LinkGeneric
10/2014
1Ciprofloxacin (Cipro)FDA LinkGeneric
10/2014
1olive leaf extractIBA
06/2014
1Immunoglobulins (Immunoglobulin)IBA
02/2014
1Myosins (Myosin)IBA
01/2014
1Indicators and Reagents (Reagents)IBA
12/2013
1Oxidoreductases (Dehydrogenase)IBA
01/2013
13-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA
01/2013
1Dexamethasone (Maxidex)FDA LinkGeneric
04/2011
1Acyclovir (Aciclovir)FDA LinkGeneric
04/2011
1Peptide Hydrolases (Proteases)FDA Link
12/2010
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
12/2010
1Small Interfering RNA (siRNA)IBA
12/2010
1CelluloseIBA
03/2008
1EnzymesIBA
03/2008
1Proteins (Proteins, Gene)FDA Link
03/2008

Therapy/Procedure

17Contact Lenses
06/2022 - 11/2008
12Therapeutics
01/2022 - 03/2008
3Drug Therapy (Chemotherapy)
06/2022 - 01/2015
3Hydrophilic Contact Lenses (Hydrophilic Contact Lens)
10/2021 - 09/2010
2Corneal Transplantation (Keratoplasty)
06/2018 - 12/2013
1Personal Protective Equipment
11/2021
1Blood Transfusion (Blood Transfusions)
06/2020
1Renal Dialysis (Hemodialysis)
11/2017
1Highly Active Antiretroviral Therapy (HAART)
11/2014
1Cryotherapy (Therapy, Cold)
12/2013
1Penetrating Keratoplasty
12/2013
1Traditional Medicine (Folk Remedies)
08/2013
1Laser In Situ Keratomileusis (LASIK)
10/2012